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Invitrogen™ CD123 Monoclonal Antibody (6H6), Alexa Fluor™ 647
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Product Code. 30565096
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100 Tests
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Pack of 100
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30565096 100 Tests Pack of 100
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Product Code. 30565096 Supplier Invitrogen™ Supplier No. MA562189

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Description

Mouse Monoclonal Antibody

CD123 Monoclonal Antibody for Flow, IHC (F), Western Blot

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD123
Applications Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone 6H6
Concentration 0.025 mg/mL
Conjugate Alexa Fluor 647
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene IL3RA
Gene Accession No. P26951
Gene Alias CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1
Gene Symbols IL3RA
Host Species Mouse
Immunogen IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3563
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1
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