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Invitrogen™ CD153 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA580170

Product Code. 15935735

  • 454.00 € / 100µg

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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - IHC: human tonsil tissue. Flow: U937 cell.

The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD153
Polyclonal
Unconjugated
Tnfsf8
CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; Cd30l; CD30-L; Cd30lg; CD30ligand; Tnfsf8; TNLG3A; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8
Rabbit
Antigen affinity chromatography
RUO
944
-20°C
Lyophilized
Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide
P32971
Tnfsf8
E.coli-derived human CD153 recombinant protein (Position: Q63-D234).
100 μg
Primary
Human
Antibody
IgG
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