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  6. CD163 Monoclonal Antibody (eBioGHI/61 (GHI/61)), eBioscience™, Invitrogen™
  7. 17150582

CD163 Monoclonal Antibody (eBioGHI/61 (GHI/61)), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1639-95

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Product Code. 17150582

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Description

Description

The eBioGHI/61 MAb reacts with human CD163 (Haemoglobin Scavenger Receptor, M130), a member of the macrophage scavenger receptor family. CD163 is expressed by tissue macrophages, circulating blood monocytes, and some reports suggest that it may also be expressed by haematopoietic progenitor cells. CD163 functions as a high affinity scavenger receptor for the complex of haemoglobin and haptoglobin which forms to clear haemoglobin from the blood. The high affinity for CD163 is specific for the haemoglobin-haptoglobin complex, whereas haemoglobin or haptoglobin display no to low affinity toward CD163. Upon ligand binding, CD163 initiates signal transduction which leads to the production of IL-6 and IL-10. Furthermore, it has been demonstrated that cytokines such as IL-6 and IL-10 can induce expression of CD163, whereas proinflammatory stimuli, such as LPS or TNF alpha, can cause shedding of a soluble form of CD163, whose function is unclear.

CD163 Monoclonal antibody specifically detects CD163 in Human samples. It is validated for Flow Cytometry, Western Blot
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD163
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q86VB7
Mouse
10 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Western Blot
eBioGHI/61 (GHI/61)
Unconjugated
CD163
Cd163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163
Affinity chromatography
RUO
9332
4° C
Liquid
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