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Invitrogen™ CD170 (Siglec F) Monoclonal Antibody (1RNM44N), NovaFluor™ Blue 660-120S, eBioscience™, Invitrogen™
Description
SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This molecule is expressed by monocytic/myeloid lineage cells. SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.
Specifications
Specifications
| Antigen | CD170 (Siglec F) |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 1RNM44N |
| Concentration | 0.1 mg/mL |
| Conjugate | NovaFluor Blue 660-120S |
| Formulation | PBS with 0.09% sodium azide; pH 7.2 |
| Gene | Siglecf |
| Gene Accession No. | Q920G3 |
| Gene Alias | CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F |
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