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Invitrogen™ CD223 Recombinant Human Monoclonal Antibody (8F6)
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Human Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA560791

Product Code. 30535698

  • 459.00 € / 100µL

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Description

Description

CD223 Recombinant Monoclonal Antibody for IHC (P), ELISA

LAG-3 is a 70-kDa surface glycoprotein in the immunoglobulin superfamily, with structural homology to CD4. It binds to MHC class II molecules with higher affinity than CD4 and is involved in the negative regulation of T cell activation and homeostatic proliferation. LAG-3 is expressed on the surface of activated T cells, including regulatory T cells, and NK cells. Notably, CD8+ T cells express LAG-3 at significantly higher levels than CD4+ T cells. Additionally, the coexpression of LAG-3 and CD49b has been proposed as a marker for identifying Type 1 regulatory T cells (Tr1 cells) in both humans and mice. This highlights LAG-3s role in immune regulation and its potential as a target for therapeutic interventions in immune-related conditions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD223
Recombinant Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
P18627
LAG3
Recombinant Human LAG3 protein.
100 μL
Primary
Human
Antibody
IgG1
ELISA, Immunohistochemistry (Paraffin)
8F6
Unconjugated
LAG3
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Human
Affinity chromatography
RUO
3902
-20°C or -80°C if preferred
Liquid
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