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  6. CD34 Mouse anti-Human, PE-Cy5, Clone: 581, BD

CD34 Mouse anti-Human, PE-Cy5, Clone: 581, BD

Mouse Monoclonal Antibody

154.08 € - 357.38 €

Specifications

Antigen CD34
Clone 581
Applications Flow Cytometry
Classification Monoclonal
Conjugate PE-Cyanine5
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BD Biosciences
561819 		25 Tests
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BD Biosciences
555823 		100 Tests
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372.00 €
357.38 € / Each
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Description

Description

The 581 monoclonal antibody specifically binds to CD34, a sialomucin-like type I transmembrane glycoprotein. This single-chain, 105-120 kDa, heavily O-glycosylated protein is expressed on hematopoietic progenitor cells, vascular endothelium, bone marrow stromal cells and embryonic fibroblasts. The cytoplasmic region of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting CD34 may play a role in signal transduction. CD34 may also play a role as an adhesion molecule since it binds to CD62E and CD62L. Clone 581 binds to the class III CD34 epitope, it is resistant to neuraminidase, chymopapain and glycoprotease. The 581 antibody blocks reactivity of another anti-CD34 monoclonal antibody, 8G12.

Specifications

Specifications

CD34
Flow Cytometry
PE-Cyanine5
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
581
Monoclonal
Mouse
Human
IgG1 κ
Affinity Purified
gp105-120; My10; Hematopoietic progenitor cell antigen CD34
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