Invitrogen™ CD96v2 Monoclonal Antibody (628226)

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

CD96v2 is a splice variant of the CD96 gene, which encodes a protein involved in the immune system, particularly in the regulation of natural killer (NK) cells and T cells. CD96, also known as Tactile, is a member of the immunoglobulin superfamily and functions as an immune checkpoint receptor. It plays a role in the adhesion and interaction between NK cells and target cells, as well as in the modulation of NK cell cytotoxic activity. The variant CD96v2 may have distinct functional properties compared to the canonical form, potentially influencing immune responses in different ways. CD96 and its variants are of significant interest in cancer immunotherapy, as they can impact tumor immune surveillance and the effectiveness of NK cell-mediated tumor cell killing. Targeting CD96, including its splice variants like CD96v2, offers a promising strategy for enhancing anti-tumor immune responses. Understanding the specific roles and mechanisms of CD96v2 in immune regulation is crucial for developing novel therapeutic approaches aimed at boosting the immune system's ability to combat cancer and other diseases.