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  6. Thermo Scientific Chemicals Cdc2-Like Kinase Inhibitor, TG003

Thermo Scientific Chemicals Cdc2-Like Kinase Inhibitor, TG003

Product Code. 15456529
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Quantity:
5 mg
50 mg
Unit Size:
50mg
5mg
Product Code. Quantity unitSize
15456529 5 mg 5mg
15466529 50 mg 50mg
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Product Code. 15456529

Brand: Thermo Scientific Chemicals J64690.#0

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Description

Cdc2-Like Kinase Inhibitor, TG003 is a benzothiazole agent that acts as a specific and ATP-competitive inhibitor of Clk family members. Reports show that TG003 modifies the regulation of alternative splicing modulated by phosphorylation of SR proteins in vitro, and rescues defects in the development of Xenopus caused by an overabundance of Clk activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TG003 is a benzothiazole agent that acts as a specific and ATP-competitive inhibitor of Clk family members.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 300801-52-9
Molecular Formula C13H15NO2S, C13H15NO2S
Synonym Clk Inhibitor; TG003

Specifications

Quantity 5 mg
Description Off-white
Content And Storage 2°C to 8°C
For Use With (Application) TG003 is a benzothiazole agent that acts as a specific and ATP-competitive inhibitor of Clk family members.
Formula Weight 249.33g/mol
Sensitivity Light Sensitive
Solubility Soluble in DMSO
Product Type Signal Transduction Reagent
Form Solid
InChI Key BGVLELSCIHASRV-UHFFFAOYSA-N
SMILES CCN1C(SC2=C1C=C(OC)C=C2)=CC(C)=O
IUPAC Name 1-(3-ethyl-5-methoxy-2,3-dihydro-1,3-benzothiazol-2-ylidene)propan-2-one
Molecular Weight (g/mol) 249.33
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Safety and Handling

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Product Identifier
  • Cdc2-Like Kinase Inhibitor, TG003
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : (Z)-1-(3-Ethyl-5-methoxy-3H-benzothiazol-2-ylidene)propan-2-one
SDS

RUO – Research Use Only

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