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CDC23 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7088179 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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Product Code. Quantity unitSize
16857223 20 μL 20µL
16847223 150 μL 150µL
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Product Code. 16857223 Supplier Proteintech Supplier No. 106831AP20UL

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Description

Rabbit Polyclonal Antibody

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.

Specifications

Antigen CDC23
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CDC23
Gene Accession No. Q8BGZ4, Q9UJX2
Gene Alias ANAPC8, APC8, CDC23, Cyclosome subunit 8
Gene Symbols Cdc23
Host Species Rabbit
Immunogen CDC23 Fusion Protein Ag1068
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291689, 52563, 8697
Target Species Rat, Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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