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Invitrogen™ CDNF Monoclonal Antibody (560108)
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Rat Monoclonal Antibody

Brand:  Invitrogen™ MA561530

Product Code. 30534441

  • 429.00 € / 100µg

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Description

Description

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CDNF
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and no preservative
Q8CC36
Cdnf
Mouse myeloma cell line NS0-derived recombinant mouse CDNF, Leu27-Leu187.
100 μg
Primary
Mouse
Antibody
IgG2a
Immunohistochemistry (Frozen)
560108
Unconjugated
Cdnf
9330140G23; arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Cdnf; Cerebral dopamine neurotrophic factor; conserved dopamine neurotrophic factor
Rat
Protein A/G
RUO
227526
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
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