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Invitrogen™ CK1 epsilon Polyclonal Antibody
Sheep Polyclonal Antibody
Brand: Invitrogen™ PA5148873
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
CSNK1E (CK1 epsilon) is a serine/threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. CSNK1E phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N-and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CKIe positively regulates Akt possibly by inhibiting PP2A. CKIe play an important role in neurodegenerative diseases.
Specifications
| CK1 epsilon | |
| Polyclonal | |
| Unconjugated | |
| CSNK1E | |
| AI426939; AI551861; AW457082; casein kinase 1; casein kinase 1 epsilon; casein kinase 1, epsilon; casein kinase I isoform epsilon; CK1e; CK1epsilon; CKI, epsilon; CKIe; CKIepsilon; CKI-epsilon; Csnk1e; HCKIE; KC1 epsilon; KC1epsilon; MGC10398; OTTHUMP00000063258; OTTHUMP00000063263; RP1-5O6.1; tau | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 1454, 27373, 58822 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| P49674, Q9JMK2 | |
| CSNK1E | |
| E. coli-derived recombinant human CK1 epsilon , Met317-Lys416. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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