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Invitrogen™ CLASP2 Polyclonal Antibody

Description
Immunogen sequence: LHNHLRNTGNG TQSSMGSPLT RPTPRSPANW SSPLTSPTN Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Specifications
Specifications
| Antigen | CLASP2 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Clasp2 |
| Gene Accession No. | O75122 |
| Gene Alias | 1500004F14Rik; 8030404L10Rik; C77448; CLASP2; CLASP2alpha; CLASP2beta; CLASP2gamma; CLIP associating protein 2; CLIP-associating protein 2; CLIP-associating protein CLASP2; cytoplasmic linker associated protein 2; cytoplasmic linker-associated protein 2; hOrbit2; Kiaa0627; mKIAA0627; multiple asters (Mast)-like homolog 2; protein Orbit homolog 2 |
| Gene Symbols | Clasp2 |
| Show More |
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