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Invitrogen™ Claudin 1 Polyclonal Antibody (MH25)

Product Code. 10313553
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Quantity:
100 μg
Unit Size:
100µg
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10313553 100 μg 100µg
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Product Code. 10313553 Supplier Invitrogen™ Supplier No. 717800

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Description

Rabbit Polyclonal Antibody

This antibody reacts with the ~ 22 kDa Claudin-1 protein. Reactivity was confirmed by western blotting and immunofluorescence. Positive controls include MDCK cells (dog), Caco-2cells (human), mouse liver, rat liver, and rat kidney. NOTE: This antibody strongly cross reacts with the Claudin-3 protein. It has been observed in western blotting inhibition studies using Caco-2 cell lysates, that this antibody is inhibited by addition of Claudin-3 peptide. For a Claudin-1 specific antibody that does not cross-react with Claudin-3, please order Cat. No. 519000 (Rb x Claudin-1) instead.

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Clone MH25
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene CLDN1
Gene Accession No. O88551, O95832, P56745
Gene Alias AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
Gene Symbols CLDN1
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminus of the human/mouse Claudin-1 protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12737, 608207, 65129, 9076
Target Species Human, Mouse, Rat, Canine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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