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Invitrogen™ COL1A1 Recombinant Rabbit Monoclonal Antibody (K01_2U53)

Rabbit Recombinant Monoclonal Antibody

287.00 € - 498.00 €

Specifications

Antigen COL1A1
Clone K01_2U53
Concentration 0.60 mg/mL
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Applications Western Blot, Immunocytochemistry
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30828583
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Invitrogen™
MA564286
100 μL
498.00 €
100µL
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30826646
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Invitrogen™
MA565745
50 μL
287.00 €
50µL
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Description

Description

Immunogen sequence: KAHDGGRYYR ADDANVVRDR DLEVDTTLKS LSQQIENIRS PEGSRKNPAR TCRDLKMCHS DWKSGEYWID PNQGCNLDAI KVFCNMETGE TCVYPTQPSV AQKNWYISKN PKDKRHVWFG ESMTDGFQFE YGGQGSDPAD VAIQLTFLRL MSTEASQNIT YHCKNSVAYM DQQTGNLKKA LLLQGSNEIE IRAEGNSRFT YSVTVDGCTS HTGAWGKTVI EYKTTKTSRL PIIDVAPLDV GAPDQE Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%, Pig - 98%, Cynomolgus monkey - 100%.

The protein encoded by this gene is the pro-alpha1 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Specifications

Specifications

COL1A1
0.60 mg/mL
Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4
P02452
1277
Recombinant protein of human Collagen I (aa 1208-1453).
Antibody
K01_2U53
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Recombinant Monoclonal
Liquid
IgG
Human
COL1A1
alpha-1 type 1 collagen; alpha-1 type I collagen; alpha1(I) procollagen; COL1A; Col1a1; Col1a-1; Cola1; Cola-1; COLIA1; Collagen 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; Collagen I; collagen of skin, tendon and bone, alpha-1 chain; collagen type I alpha 1; collagen, type 1, alpha 1; collagen, type I, alpha 1; Collagen1A1; EDSC; Mov13; Mov-13; OI1; OI2; OI3; OI4; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; Type I Collagen; type I proalpha 1; type I procollagen alpha 1 chain; type I-alpha 1 collagen
COL1A1
Primary
Protein A/G
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