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CSF2 Mouse anti-Human, Clone: OTI8G5, liquid, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies TA808009
Additional Details : Weight : 0.05000kg
Description
GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombit GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).Specifications
CSF2 | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P04141 | |
CSF2 | |
Human recombit protein fragment corresponding to amino acids 18-144 of human CSF2 produced in E.coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunohistochemistry (Paraffin), Western Blot | |
OTI8G5 | |
Unconjugated | |
CSF2 | |
CSF, GMCSF | |
Mouse | |
Affinity Chromatography | |
RUO | |
1437 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |