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  6. Cytokeratin 17 Antibody (E3 (same as Ks17.E3)), Novus Biologicals™
  7. 18083624

Cytokeratin 17 Antibody (E3 (same as Ks17.E3)), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 2 publications

Brand:  Novus Biologicals NBP2-29421

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Product Code. 18083624

  • 595.00 € / 0.10mg

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Description

Description

Cytokeratin 17 Monoclonal specifically detects Cytokeratin 17 in Human, Rat, Porcine, Bovine, Goat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cytokeratin 17
Monoclonal
0.2 mg/ml
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1
Mouse
46 kDa
0.1 mg
Cancer
3872
Human, Rat, Pig, Bovine, Goat
Purified
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
E3 (same as Ks17.E3)
Unconjugated
Q04695
KRT17
Cytoskeletal fraction of rat colon epithelium (Uniprot: Q04695)
Protein A or G purified
RUO
Primary
Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as 'epithelial stem cell' marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
Store at 4C.
IgG2b κ
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