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Cytokeratin, HMW Antibody (AE-3), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

286.00 € - 552.00 €

Specifications

Antigen Cytokeratin, HMW
Clone AE-3
Concentration 0.2 mg/ml
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18424112
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Novus Biologicals
NBP2-29404-20ug
20 ug
286.00 €
20µg
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18196032
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Novus Biologicals
NBP2-29404
0.1 mg
552.00 €
0.10mg
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Description

Description

Cytokeratin, HMW Monoclonal specifically detects Cytokeratin, HMW in Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Rabbit samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Specifications

Specifications

Cytokeratin, HMW
0.2 mg/ml
Monoclonal
Purified
RUO
Q01546
51350
Human epidermal keratin (Uniprot: Q01546)
Primary
Store at 4C.
AE-3
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Unconjugated
Mouse
Human, Mouse, Rat, Bovine, Canine, Chicken, Primate, Rabbit
CK-2P, cytokeratin 2, Cytokeratin-2P, HUMCYT2A, K2P, K76, keratin 76, keratin, type II cytoskeletal 2 oral, Keratin-76, KRT2Bcytokeratin-2P, KRT2Pkeratin 2p, KRT76, Type-II keratin Kb9
KRT76
IgG1 κ
Protein A or G purified
This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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