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Dabrafenib, MedChemExpress

Product Code. p-200096105
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16482257 50 mg 50mg
16468727 5 mg 5mg
16451136 200 mg 200mg
16416128 10 mg 10mg
15750389 100 mg 100mg
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Product Code. 16482257 Supplier Medchem Express Supplier No. HY14660

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Description

MedChemExpress Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

Specifications

Chemical Name or Material Dabrafenib
CAS 1195765-45-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C23H20F3N5O2S2
Quantity 50 mg
Synonym GSK2118436A GSK2118436
Solubility Information DMSO : ≥ 33 mg/mL (63.52 mM)
SMILES CC(C)(C)C1=NC(C2=C(F)C(NS(C3=C(F)C=CC=C3F)(=O)=O)=CC=C2)=C(C4=CC=NC(N)=N4)S1
Molecular Weight (g/mol) 519.56
Formula Weight 519.56
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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