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Invitrogen™ DAPK1 Recombinant Rabbit Monoclonal Antibody (23GB3565), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA552616
This item is not returnable.
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Description
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
Specifications
| DAPK1 | |
| Recombinant Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P53355, Q80YE7 | |
| DAPK1 | |
| A synthetic peptide of human DAP Kinase 1 (300-350AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB3565 | |
| Unconjugated | |
| DAPK1 | |
| D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 1612, 306722, 69635 | |
| -20°C | |
| Liquid |
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