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DDIT3 Monoclonal Antibody (OTI3H7), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA802210
This item is not returnable.
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Description
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.Specifications
| DDIT3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P35638 | |
| DDIT3 | |
| Full length human recombit protein of human DDIT3 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI3H7 | |
| Unconjugated | |
| DDIT3 | |
| C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 1649 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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