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Invitrogen™ Desmoglein 2 (DSG2) Polyclonal Antibody

Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human HepG2 whole cell, human A549 whole cell, rat heart tissue, mouse heart tissue. IHC: human breast carcinoma tissue, human lung cancer tissue, rat intestine tissue. ICC/IF: MCF-7 cell. Flow: 293T cell.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Specifications
Specifications
| Antigen | Desmoglein 2 (DSG2) |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 500 μg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal |
| Gene | DSG2 |
| Gene Accession No. | O55111, Q14126 |
| Gene Alias | AA408168; ARVC10; ARVD10; Cadherin family member 5; CDHF5; CMD1BB; D18Ertd293e; desmoglein 2; desmoglein-2; DSG2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037 |
| Gene Symbols | DSG2 |
| Show More |
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