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  7. 18196742

DOG1/TMEM16A Antibody (SPM580), Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-32841-0.1MG

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Product Code. 18196742

  • 509.00 € / 0.10mg

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Description

Description

DOG1/TMEM16A Monoclonal specifically detects DOG1/TMEM16A in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DOG1/TMEM16A
Monoclonal
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Mouse
114 kDa
0.1 mg
Primary
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
Store at 4C.
IgG1 κ
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
SPM580
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, Immunocytochemistry
Q5XXA6
ANO1
Recombinant human DOG-1 protein
Protein A purified
RUO
55107
Human
Purified
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