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  6. Doxorubicin hydrochloride, MedChemExpress

Doxorubicin hydrochloride, MedChemExpress

Product Code. 16452437
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16451756 500 mg 500mg
16421166 200 mg 200mg
16406646 100 mg 100mg
16431479 1 g 1g
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Product Code. 16452437 Supplier Medchem Express Supplier No. HY15142

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Description

MedChemExpress Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.

Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.

Specifications

Chemical Name or Material Doxorubicin hydrochloride
Physical Form Solid
CAS 25316-40-9
Color Reddish Brown
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C27H30ClNO11
For Use With (Application) Cancer-Kinase/protease
Synonym Hydroxydaunorubicin hydrochloride
Solubility Information DMSO : 35.71 mg/mL (61.57 mM; ultrasonic and warming and heat to 60°C) ∣H2O : 20 mg/mL (34.48 mM; Need ultrasonic)
SMILES COC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl
Molecular Weight (g/mol) 579.98
Formula Weight 579.98
Percent Purity 95.0%
Grade Research
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Safety and Handling

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Product Identifier
  • Doxorubicin (hydrochloride)
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 1A
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
 Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H350-May cause cancer.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P202-Do not handle until all safety precautions have been read and understood.
  • P264-Wash hands thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P313-Get medical advice/attention.
  • P321-Specific treatment (see on this label).
  • P330-Rinse mouth.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362-Take off contaminated clothing.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Hydroxydaunorubicin(hydrochloride)

Research purposes only

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