Learn More
Description
Doxycycline Hydrochloride is a synthetic oxytetracycline derivative and is a member of the tetracycline antibiotics group. It shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metallo-proteinases), such as type 1 collagenase. It is used to treat a variety of infections and for other biomedical applications.
- Treats chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections
- Inhibits the inflammatory response of Lyme disease
- Used in prophylaxis of anthrax (caused by Bacillus anthracis)
- Effective against Yersinia pestis
- Inhibits collagen synthesis
- Used in studies on wound healing and tissue remodeling
- Eliminates Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs
- Eliminates Ixodes scapularis ticks
Specifications
Specifications
| Physical Form | Powder |
| CAS | 10592-13-9 |
| Concentration | Working Concentration: It is typically used at a concentration of 20ug/mL and is stable in media at 37°C for approximately 5 days. |
| Quantity | 10 g |
| Molecular Formula | C22H25ClN2O8 |
| MDL Number | MFCD03427564 |
| Synonym | Biocamycin, Doxigalumicina, Doxycycline hyclate, Doxy-II, Midoxin, Novadox, Retens, Tetradox, Vibradox, Hydramycin, 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride |
| Solubility Information | Soluble in water (10mg/mL, clear, yellowish to yellowish-green solution) and DMSO (50mg/mL). |
| InChI Key | VLUQVUWDECWBTL-UQVCFKGQSA-N |
| SMILES | [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12 |
| Vedi altri risultati |
Sicurezza e movimentazione
- Doxycycline Hydrochloride
- Warning
- Acute toxicity Category 4
- Skin corrosion/irritation Category 2
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
- H302+H312-Harmful if swallowed or in contact with skin
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321-Specific treatment (see on this label).
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.