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Invitrogen™ EAPP Monoclonal Antibody (1E4)
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Product Code. 15364331
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Quantity:
100 μL
Unit Size:
100µL
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15364331 100 μL 100µL
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Product Code. 15364331 Supplier Invitrogen™ Supplier No. MA518062

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Mouse Monoclonal Antibody

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This protein may play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The C-terminal of EAPP binds the N-terminal of E2F1 and also interacts with E2F2 and E2F3, but not E2F4.
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Specifications

Antigen EAPP
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1E4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene EAPP
Gene Accession No. Q56P03, Q5BU09
Gene Alias 1810011O16Rik; BM036; BM-036; c14orf11; E2F associated phosphoprotein; E2F-associated phosphoprotein; Eapp; hypothetical protein LOC327318; RGD1309624; Unknown (protein for MGC:139672); wu:fd21g02; zgc:65820
Gene Symbols EAPP
Host Species Mouse
Immunogen N-terminal fragment of human EAPP (Immunogen sequence: 1-266).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55837, 66266
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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