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Endoglin/CD105, Rabbit anti-Mouse, Clone: MJ7/18, Novus Biologicals™
Rabbit Monoclonal Antibody
Brand: Novus Biologicals NBP2-81085-0.025MG
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Description
Endoglin/CD105 Monoclonal specifically detects Endoglin/CD105 in Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation.
Specifications
| Endoglin/CD105 | |
| Monoclonal | |
| 1 mg/mL | |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation | |
| CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1 | |
| Rabbit | |
| Protein A purified | |
| RUO | |
| Primary | |
| MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells. | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. | |
| IgG κ |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation | |
| MJ7/18 | |
| Unconjugated | |
| PBS | |
| ENG | |
| MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells. | |
| 0.025 mg | |
| Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers | |
| 2022 | |
| Mouse | |
| Purified |
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