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Invitrogen™ EpoR Recombinant Rabbit Monoclonal Antibody (4O8U2)
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Rabbit Recombinant Monoclonal Antibody

176.00 € - 436.00 €

Specifications

Antigen EpoR
Clone 4O8U2
Concentration 1.06 mg/mL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Applications ELISA, Western Blot
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30284046
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Invitrogen™
MA557949
20 μL
176.00 €
20µL
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30284654
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Invitrogen™
MA557950
100 μL
436.00 €
100µL
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Description

Description

Immunogen sequence: APPPNLPDPK FESKAALLAA RGPEELLCFT ERLEDLVCFW EEAASAGVGP GNYSFSYQLE DEPWKLCRLH QAPTARGAVR FWCSLPTADT SSFVPLELRV TAASGAPRYH RVIHINEVVL LDAPVGLVAR LADESGHVVL RWLPPPETPM TSHIRYEVDV SAGNGAGSVQ RVEILEGRTE CVLSNLRGRT RYTFAVRARM AEPSFGGFWS AWSEPVSLLT PSDLD.

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
Specifications

Specifications

EpoR
1.06 mg/mL
ELISA, Western Blot
Unconjugated
Rabbit
RUO
PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
P19235
2057
Recombinant protein (or fragment).
Antibody
4O8U2
-20°C, Avoid Freeze/Thaw Cycles
Recombinant Monoclonal
Liquid
IgG
Human
EPOR
EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR
EPOR
Primary
Protein A
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