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ERCC1 Monoclonal Antibody (OTI5A2), TrueMAB™, OriGene

Product Code. 17531582
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100 μL
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17531582 100 μL 100µL
17551582 30 μL 30µL
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Product Code. 17531582 Supplier Origene Technologies Supplier No. TA504405

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Description

Mouse Monoclonal Antibody

The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3′ of the DNA lesion while the ERCC1-XPF complex makes the 5′ incision.

Specifications

Antigen ERCC1
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI5A2
Concentration 0.64 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ERCC1
Gene Accession No. P07992
Gene Alias COFS4, RAD10, UV20
Gene Symbols ERCC1
Host Species Mouse
Immunogen Full length human recombit protein of human ERCC1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2067
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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