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  6. Invitrogen™ EYA2 Recombinant Rabbit Monoclonal Antibody (23GB5350), Invitrogen™

Invitrogen™ EYA2 Recombinant Rabbit Monoclonal Antibody (23GB5350), Invitrogen™
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Product Code. p-200087939
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100 μL
Unit Size:
100µL
20µL
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Product Code. Quantity unitSize
30087519 100 μL 100µL
30088467 20 μL 20µL
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Product Code. 30087519 Supplier Invitrogen™ Supplier No. MA552842

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Description

Rabbit Recombinant Monoclonal Antibody

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr- 142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EYA2
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB5350
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EYA2
Gene Accession No. O00167, O08575
Gene Alias Drosophila-type eyes absent 2-like protein; Eab1; EYA transcriptional coactivator and phosphatase 2; Eya2; eyes absent 2; eyes absent 2 homolog; eyes absent 2 homolog (Drosophila); eyes absent 2 isoform a; eyes absent homolog 2
Gene Symbols EYA2
Host Species Rabbit
Immunogen A synthesized peptide derived from human EYA2 (20-50AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14049, 2139
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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