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Invitrogen™ Factor VII Monoclonal Antibody (406707)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561292
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
Specifications
| Factor VII | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P70375 | |
| F7 | |
| Chinese hamster ovary cell line CHO-derived recombinant human mouse Coagulation Factor VII, Ala42-Leu446. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Frozen), Western Blot | |
| 406707 | |
| Unconjugated | |
| F7 | |
| AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA | |
| Rat | |
| Protein A/G | |
| RUO | |
| 14068 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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