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Invitrogen™ Factor VII Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5115207
This item is not returnable.
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Description
Antibody detects endogenous levels of total Factor VII.
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
Specifications
| Factor VII | |
| Polyclonal | |
| Unconjugated | |
| F7 | |
| AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 14068, 2155, 260320 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P08709, P70375, Q8K3U6 | |
| F7 | |
| A synthesized peptide derived from human F7(Accession P08709), corresponding to amino acid residues C187-L237. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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