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Fibrinogen Monoclonal Antibody (UC45), Invitrogen™

Product Code. 10560634
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Quantity:
100 μg
Unit Size:
100µg
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10560634 100 μg 100µg
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Product Code. 10560634 Supplier Invitrogen Supplier No. MA126074

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Description

Mouse Monoclonal Antibody

MA1-26074 detects alpha Fibrin from human samples. MA1-26074 reacts very strongly with the alpha chain of human fibrinogen. MA1-26074 has been successfully used in radioimmune assay and immunocytochemistry procedures. The MA1-26074 immunogen is human acute monoblastic leukemia cells.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibrinogen
Applications Immunocytochemistry, Immunofluorescence, Radioimmune Assays (RIA)
Classification Monoclonal
Clone UC45
Concentration 1 mg/mL
Conjugate Unconjugated
Gene FGA
Gene Accession No. P02671
Gene Symbols FGA
Host Species Mouse
Immunogen Human acute monoblastic leukemia cells.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2243
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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