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  6. Filaggrin Antibody (FLG/1561), Novus Biologicals™

Filaggrin Antibody (FLG/1561), Novus Biologicals™

Mouse Monoclonal Antibody

302.00 € - 543.00 €

Specifications

Antigen Filaggrin
Clone FLG/1561
Concentration 0.2 mg/mL
Dilution Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
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Novus Biologicals
NBP2-53243-20UG 		20 μg
302.00 €
20µg
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18289260
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Novus Biologicals
NBP2-53243-100UG 		100 μg
543.00 €
100µg
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Description

Description

Filaggrin Monoclonal specifically detects Filaggrin in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
Specifications

Specifications

Filaggrin
0.2 mg/mL
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Unconjugated
Mouse
Cytoskeleton Markers
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
2312
Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Primary
Store at 4C.
FLG/1561
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Monoclonal
Purified
RUO
Human
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
FLG
IgG1
Protein A or G purified
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery
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