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G418 disulfate, 50mg/ml solution

Produktkod. 15436029
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Produktkod. 15436029 Leverantör Thermo Scientific Alfa Aesar Leverantörsnummer J63871.AB
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G418 sulfate, geneticin, CAS # 108321-42-2, is an antibiotic closely related to Gentamicin B, the common aminoglycoside antibiotic. | CAS: 108321-42-2 | C20H44N4O18S2 | 692.70 g/mol

G418 disulfate is used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene. Optimal concentrations for selection and maintenance vary by cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • G418 sulfate (geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea
  • G418 is bacteriostatic that prevents polypeptide formation by inhibiting the elongation step of polypeptide synthesis

Applications

  • G418 sulfate can be used for the selection of genetically engineered cells in both eukaryotes and prokaryotes
  • Laboratory-grade for applications such as biochemistry
TRUSTED_SUSTAINABILITY

Kemiska identifierare

CAS 108321-42-2
Molecular Formula C20H44N4O18S2
Molecular Weight (g/mol) 692.70
MDL Number MFCD00058314
InChI Key UHEPSJJJMTWUCP-KETIWVBHNA-N
Synonym Geneticin
PubChem CID 134129582
IUPAC Name (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-2-(1-hydroxyethyl)oxane-3,4-diol; bis(sulfuric acid)
SMILES OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O

Specifikationer

Type G418 Disulfate
Physical Form Liquid
Color Undesignated
Concentration 50mg/ml solution
Quantity 10 mL
Solubility Information Difficult to mix.
Formula Weight 692.71
Chemical Name or Material G418 disulfate
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Produktbeteckning
  • G418 disulfate, 50mg/ml solution
Signalord
  • Danger
Riskkategorier
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
Faroangivelser
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Skyddsangivelse
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-[In case of inadequate ventilation] wear respiratory protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
Kompletterande information
  • MIXTURE LIST-Contain: G418 disulfate

RUO – Research Use Only

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