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Invitrogen™ Glutaredoxin 2 Polyclonal Antibody
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Product Code. 15974885
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100 μg
Unit Size:
100µg
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15974885 100 μg 100µg
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Product Code. 15974885 Supplier Invitrogen™ Supplier No. PA579316

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A549 whole cell, rat lung tissue, mouse lung tissue. IHC: Rat Brain tissue, human lung cancer tissue, human mammary cancer tissue.

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glutaredoxin 2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.01mg sodium azide, 0.05mg thimerosal
Gene GLRX2
Gene Accession No. Q6AXW1, Q923X4, Q9NS18
Gene Alias 1700010P22Rik; AI645710; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; GLRX2; glutaredoxin (thioltransferase) 2; glutaredoxin 2; glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial; GRX2
Gene Symbols GLRX2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human Glutaredoxin 2 (103-119aa EYGNQFQDALYKMTGER).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114022, 51022, 69367
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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