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  6. GTPBP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

GTPBP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16808723 Shop All Proteintech Products
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150 μL
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20µL
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16808723 150 μL 150µL
16818723 20 μL 20µL
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Product Code. 16808723 Supplier Proteintech Supplier No. 115571AP150UL

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Description

Rabbit Polyclonal Antibody

Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein that is expressed in kidney, skeletal muscle, testis, brain and thymus, though it is not detected in liver. Expression of GTPBP2 is enhanced by ©-interferon stimulation in HeLa cells, THP-1 cells and thioglycollate-elicited mouse peritoneal macrophages. There are four isoforms of GTPBP2 that are expressed as a result of alternative splicing events. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities.

Specifications

Antigen GTPBP2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene GTPBP2
Gene Accession No. Q3UJK4, Q9BX10
Gene Alias GTP binding protein 2, GTPBP2
Gene Symbols Gtpbp2
Host Species Rabbit
Immunogen GTPBP2 Fusion Protein Ag2113
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 363195, 54676, 56055
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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