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Invitrogen™ IFN beta Recombinant Rabbit Monoclonal Antibody (6K0L7)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA557880
This item is not returnable.
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Description
Immunogen sequence: MNNRWILHAA FLLCFSTTAL SINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN.
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Specifications
| IFN beta | |
| Recombinant Monoclonal | |
| 0.9 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| P01575 | |
| Ifnb1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of mouse IFN-beta (NP_034640.1). | |
| 100 μL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 6K0L7 | |
| Unconjugated | |
| Ifnb1 | |
| Fibroblast interferon; Ifb; IFF; IFN b; IFN β; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNβ; Interferon; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 15977 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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