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IFNAR2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10522-1-AP-150UL

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Product Code. 16806963

  • 410.00 € / 150µL

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Description

Description

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
Specifications

Specifications

IFNAR2
Polyclonal
Unconjugated
IFNAR2
IFN alpha REC, IFN alpha/beta receptor 2, IFN R, IFN R 2, IFNABR, IFNAR2, IFNARB, Type I interferon receptor 2
Rabbit
Antigen Affinity Chromatography
RUO
3455
-20°C
Liquid
Flow Cytometry, Western Blot
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P48551
IFNAR2
IFNAR2 Fusion Protein Ag0191
150 μL
Primary
Human
Antibody
IgG
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