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IgE Monoclonal Antibody (Ige21), NovaFluor™ Blue 660-120S, eBioscience™, Invitrogen™

Product Code. p-200020256
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25 Tests
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18735475 100 Tests Pack of 100
18735385 25 Tests Pack of 25
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Product Code. 18735475 Supplier Invitrogen Supplier No. H077T03B08

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Mouse Monoclonal Antibody

IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations. IgE is also functionally important for immunity against parasites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IgE
Applications Flow Cytometry
Classification Monoclonal
Clone Ige21
Concentration 0.2 μg/Test
Conjugate NovaFluor Blue 660-120S
Formulation PBS with 0.09% sodium azide, pH 13.2
Gene IGHE
Gene Accession No. P01854
Gene Alias HCAK1, IgA1, IgG3, IGHA1, IGHA2, IGHG1, IGHG2, IGHG3, IGHG4, IGKC, IGKCD, IGLC, IGLC1, Immunoglobulin E, immunoglobulin heavy constant alpha 1, immunoglobulin heavy constant alpha 2 (A2m marker), immunoglobulin heavy constant gamma 1 (G1m marker), immunoglobulin heavy constant gamma 2 (G2m marker), immunoglobulin heavy constant gamma 3 (G3m marker), immunoglobulin heavy constant gamma 4 (G4m marker), immunoglobulin kappa constant, immunoglobulin lambda constant 1, ImmunoglobulinE, Km
Gene Symbols IGHE
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3497
Target Species Human
Content And Storage 4°, C, store in dark, DO NOT FREEZE!
Form Liquid
Isotype IgG1 κ
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