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IgE Monoclonal Antibody (Ige21), NovaFluor™ Blue 660-120S, eBioscience™, Invitrogen™
Description
IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations. IgE is also functionally important for immunity against parasites.
Specifications
Specifications
| Antigen | IgE |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | Ige21 |
| Concentration | 0.2 μg/Test |
| Conjugate | NovaFluor Blue 660-120S |
| Formulation | PBS with 0.09% sodium azide, pH 13.2 |
| Gene | IGHE |
| Gene Accession No. | P01854 |
| Gene Alias | HCAK1, IgA1, IgG3, IGHA1, IGHA2, IGHG1, IGHG2, IGHG3, IGHG4, IGKC, IGKCD, IGLC, IGLC1, Immunoglobulin E, immunoglobulin heavy constant alpha 1, immunoglobulin heavy constant alpha 2 (A2m marker), immunoglobulin heavy constant gamma 1 (G1m marker), immunoglobulin heavy constant gamma 2 (G2m marker), immunoglobulin heavy constant gamma 3 (G3m marker), immunoglobulin heavy constant gamma 4 (G4m marker), immunoglobulin kappa constant, immunoglobulin lambda constant 1, ImmunoglobulinE, Km |
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