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Invitrogen™ IL17RB Monoclonal Antibody (152309)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA560884
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
Specifications
| IL17RB | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q9JIP3 | |
| IL17RB | |
| Mouse myeloma cell line NS0-derived recombinant mouse IL-17 RB, Arg18-Gly286 (predicted). | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| ELISA, Western Blot | |
| 152309 | |
| Unconjugated | |
| IL17RB | |
| CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7 | |
| Rat | |
| Protein A/G | |
| RUO | |
| 50905 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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