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Invitrogen™ IL4R Polyclonal Antibody
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Product Code. 30535843
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
30535843 100 μg 100µg
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Product Code. 30535843 Supplier Invitrogen™ Supplier No. PA5149259

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Description

Sheep Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL4R
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene IL4R
Gene Accession No. P24394
Gene Alias 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Gene Symbols IL4R
Host Species Sheep
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-4 R alpha , Gly24-His232.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3566
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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