Invitrogen™ Influenza B NP Recombinant Rabbit Monoclonal Antibody (004)

Description

Widely recognize Influenza B Nucleoprotein. Has cross-reactivity in ELISA and WB with: Influenza B (B/Austria/1359417/2021) NP Protein; Influenza B (B/Brisbane/60/2008) NP; Influenza B (B/Colorado/06/2017) NP; Influenza B (B/Florida/4/2006) NP; Influenza B (B/Phuket/3073/2013) NP; Influenza B (B/Washington/02/2019) NP. Has cross-reactivity in ELISA with: Influenza B (B/Victoria/705/2018) NP; No cross-reactivity in ELISA and WB with: H1N1 (A/Brevig Mission/1/1918) NP; H1N1 (A/Brisbane/02/2018 NP; H1N1 (A/California/07/2009) NP; H1N1 (A/Guangdong-Maonan/SWL1536/2019) NP; H1N1 (A/Hawaii/70/2019) NP; H1N1 (A/Michigan/45/2015 NP; H1N1 (A/Puerto Rico/8/34/Mount Sinai) NP (I116M); H1N1 (A/Victoria/2570/2019)/(A/Wisconsin/588/2019) NP; H2N2 (A/Ann Arbor/6/1960) NP; H3N2 (A/Aichi/2/1968) NP; H3N2 (A/Cambodia/e0826360/2020 (H3N2)-like NP; H3N2 (A/Hong Kong/1/1968) NP; H3N2 (A/Hong Kong/2671/2019) NP; H3N2 (A/Hong Kong/45/2019) NP; H3N2 (A/Hong Kong/4801/2014) NP; H3N2 (A/Kansas/14/2017) NP; H3N2 (A/Switzerland/9715293/2013) NP; H5N1 (A/Texas/37/2024) NP Protein; H7N9 (A/Anhui/1-BALF_RG6/2013) NP; H7N9 (A/Shanghai/2/2013) NP; No cross-reactivity in ELISA with: H1N1 (A/Victoria/2454/2019) NP; SARS-CoV-2 Nucleocapsid Protein; HCoV-229E Nucleocapsid Protein HCoV-NL63 Nucleocapsid Protein; HCoV-HKU1 Nucleocapsid Protein; HCoV-OC43 Nucleocapsid Protein; No cross-reactivity in WB with: H3N2 (A/Darwin/9/2021)/(A/Darwin/6/2021) NP Protein.

Influenza A and B are the two types of influenza viruses that cause epidemic human disease. Influenza B viruses currently circulating are divided into two antigenically and genetically distinct groups: the Victoria and Yamagata lineages. Influenza virus B is a genus in the virus family Orthomyxoviridae. A limited host range means that Influenza virus B pandemics are rare. The nucleoprotein protects the negative strand viral RNA from nucleases by encapsidating it. Encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.