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Invitrogen™ Integrin beta 7 Monoclonal Antibody (332428)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561253
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications
| Integrin beta 7 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P26011 | |
| ITGB7 | |
| Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin B7, Glu20-His722. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 332428 | |
| Unconjugated | |
| ITGB7 | |
| Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen | |
| Rat | |
| Protein A/G | |
| RUO | |
| 16421 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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