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Kenpaullone, MedChemExpress

Product Code. 16471317
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Product Code. 16471317 Supplier Medchem Express Supplier No. HY12302

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Description

MedChemExpress Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC50s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro.

Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β, with IC50s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC50s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4, reduces self-renewal of breast cancer stem cells and cell motility in vitro.

Specifications

Chemical Name or Material Kenpaullone
CAS 142273-20-9
Color Off-white to yellow
Purity Grade Notes Research
Molecular Formula C16H11BrN2O
Quantity 50 mg
Synonym 9-Bromopaullone NSC-664704
Solubility Information DMSO : ≥ 35 mg/mL (106.97 mM)
SMILES O=C1NC2=CC=CC=C2C(NC3=C4C=C(Br)C=C3)=C4C1
Molecular Weight (g/mol) 327.18
Formula Weight 327.18
Percent Purity 98.01%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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