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Invitrogen™ KIR3DL2 Recombinant Human Monoclonal Antibody (8D10)
Human Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA560726
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Description
KIR3DL2 Recombinant Monoclonal Antibody for Flow, ELISA
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals.
Specifications
| KIR3DL2 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4 | |
| P43630 | |
| Kir3dl2 | |
| Recombinant Human KIR3DL2 protein. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Flow Cytometry | |
| 8D10 | |
| Unconjugated | |
| Kir3dl2 | |
| 3DL2; CD158 antigen-like family member K; CD158K; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2; killer cell immunoglobulin-like receptor 3DL2; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2; killer Ig receptor; killer immunoglobulin-like receptor-like 2; killer-cell immunoglobulin-like receptor; killer-cell immunoglobulin-like receptor 3DL2; KIR antigen 3DL2; KIR3DL2; KIR-3DL2; Kirl2; KIR-like receptor 2; LOC727787; MHC class I NK cell receptor; natural killer cell receptor; natural killer-associated transcript 4; NKAT4; NKAT-4; NKAT4B; p140; p70 killer cell inhibitory receptor; p70 natural killer cell receptor clone CL-5; p70 NK receptor CL-5 | |
| Human | |
| Affinity chromatography | |
| RUO | |
| 3812 | |
| -20°C or -80°C if preferred | |
| Liquid |
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