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Invitrogen™ KV1.1 (KCNA1) Polyclonal Antibody
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Code produit 16659134
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Quantity:
100 μL
Conditionnement:
100µL
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Code produit Quantity unitSize
16659134 100 μL 100µL
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Code produit 16659134 Fournisseur Invitrogen™ Code fournisseur PA5102673

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total KCNA1.

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia.
TRUSTED_SUSTAINABILITY

Spécification

Antigen KV1.1 (KCNA1)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Kcna1
Gene Accession No. P10499, P16388, Q09470
Gene Alias AEMK; AI840627; brain potassium channel protein-1; EA1; HBK1; HUK1; IA; Kca1-1; Kcna; Kcna1; Kcpvd; Kv1.1; MBK1; mceph; megencephaly; MGC126782; MGC138385; MK1; Mk-1; MKI; potassium (K+) channel protein voltage dependent; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage gated channel shaker related subfamily member 1; potassium voltage gated channel, shaker related subfamily, member 1; potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); RBK1; RBKI; RCK1; Shak; Voltage-gated K(+) channel HuKI; voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
Gene Symbols Kcna1
Host Species Rabbit
Immunogen A synthesized peptide derived from human KCNA1(Accession Q09470), corresponding to amino acid residues E420-Q470.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16485, 24520, 3736
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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