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CD117/c-Kit/SCF-Receptor Rabbit Polyclonal Antibody, Epredia™

Optimize staining of formalin-fixed, paraffin-embedded tissues with Epredia™ CD117/c-Kit/SCF-Receptor, Rabbit Polyclonal Antibody.

Brand:  Epredia RB-9038-P1

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Product Code. 12673387

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Description

Description

Recognizes a protein of 145kDa, which is identified as CD117/p145kit. This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit. It precipitates both the unoccupied as well as the occupied form of c-kit. The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis. This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Dog. Others not tested

Epitope: Cytoplasmic domain

Immunogen: A synthetic peptide from the cytoplasmic domain of human CD117/c-kit protein

Molecular Weight: 145 kDa

Positive Control: Stromal tumor, skin or tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD117/c-Kit/SCF-Receptor
Polyclonal
Unconjugated
A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein
IVD
Canine
IgG
Immunohistochemistry (Paraffin)
200µg/mL
Rabbit
500 μL
Primary
Concentrated
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