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  7. 12610007

PTEN/MMAC1 Ab-4 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ PTEN/MMAC1 Ab-4, Mouse Monoclonal Antibody.

Brand:  Epredia MS-1601-S0

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Product Code. 12610007

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Description

Description

PTEN/MMAC1, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling.

Host Species: Mouse

Clone: 17.A

Isotype: IgM/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human PTEN protein

Molecular Weight: 60kDa

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY
Specifications

Specifications

PTEN/MMAC1 Ab-4
Monoclonal
Unconjugated
Recombinant human PTEN protein
RUO
Primary
Concentrated
Immunohistochemistry (Paraffin)
17.A
Mouse
100 μL
Cancer and Tumor Biology
Human
IgM κ
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