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  8. Lapatinib ditosylate, MedChemExpress

Lapatinib ditosylate, MedChemExpress

Product Code. 16461949
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Product Code. 16461949 Supplier Medchem Express Supplier No. HY50898A

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Description

MedChemExpress Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

Specifications

Chemical Name or Material Lapatinib ditosylate
CAS 388082-77-7
Color Yellow
Purity Grade Notes Research
Molecular Formula C43H42ClFN4O10S3
Quantity 1 g
Synonym GW572016 ditosylateGW2016 ditosylate
Solubility Information DMSO : 125 mg/mL (135.07 mM; Need ultrasonic)
SMILES O=S(CCNCC1=CC=C(C2=CC=C3C(C(NC4=CC(Cl)=C(C=C4)OCC5=CC(F)=CC=C5)=NC=N3)=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O
Molecular Weight (g/mol) 925.46
Formula Weight 925.46
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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