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Larotrectinib sulfate, MedChemExpress

Product Code. 16461597
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Product Code. 16461597

Brand: Medchem Express HY12866A

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Description

MedChemExpress Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).

Larotrectinib sulfate (LOXO-101 sulfate

Specifications

Chemical Name or Material Larotrectinib sulfate
CAS 1223405-08-0
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H24F2N6O6S
Quantity 50 mg
Synonym LOXO-101 sulfateARRY-470 sulfate
Solubility Information DMSO : 50 mg/mL (94.96 mM; Need ultrasonic) ∣H2O : 2 mg/mL (3.80 mM; ultrasonic and adjust pH to 2 with 1M HCl)
SMILES O=S(O)(O)=O.O=C(N1CC[C@H](O)C1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2
Molecular Weight (g/mol) 526.51
Formula Weight 526.51
Percent Purity 98.69%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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